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Oropouche Virus: A Rising Threat in the Western Hemisphere

Oropouche Virus: A Rising Threat in the Western Hemisphere

Lead Author: Kevin O’Laughlin

Journal

Annals of Internal Medicine

DOI

https://doi.org/10.7326/ANNALS-24-03049

Abstract

Oropouche virus (OROV), a single-stranded, negative-sense RNA virus in the Simbu serogroup of the genus Orthobunyavirus, is a cause of acute febrile illness in humans. Oropouche virus disease, also referred to as Oropouche fever or sloth fever, was first detected in 1955 in a 24-year-old forest worker in Oropouche de Vega, a village near Sangre Grande on the island of Trinidad. The virus is transmitted to humans primarily by the biting midge Culicoides paraensis , but Culex quinquefasciatus mosquitoes may also play a role in transmission.