We would like to alert the Network to reports of severe hepatitis of unknown origin in children under the age of 10. The first reports were from the UK, but nearly 100 cases have now been reported from several European countries, as well as the state of Alabama in the United States. Reported presentations generally include jaundice, and non-specific gastrointestinal symptoms, with hepatic enzymes more than 10-fold above normal. Fever is uncommon. No relationship to SARS-CoV-2 infection or vaccination is evident. Some cases reportedly tested positive for adenovirus, although it is not specified what type of test was performed. The epidemiology of the cases reportedly suggests an infectious etiology, although details were not given explaining this assumption.
We encourage out sites to report any suspicious cases to their local public health authorities, and also to geosentinel@geosentinel.org so that the OPI can disseminate any important information to the Network.
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We would like to alert the Network to reports of severe hepatitis of unknown origin in children under the age of 10. The first reports were from the UK, but nearly 100 cases have now been reported from several European countries, as well as the state of Alabama in the United States. Reported presentations generally include jaundice, and non-specific gastrointestinal symptoms, with hepatic enzymes more than 10-fold above normal. Fever is uncommon. No relationship to SARS-CoV-2 infection or vaccination is evident. Some cases reportedly tested positive for adenovirus, although it is not specified what type of test was performed. The epidemiology of the cases reportedly suggests an infectious etiology, although details were not given explaining this assumption.
We encourage out sites to report any suspicious cases to their local public health authorities, and also to geosentinel@geosentinel.org so that the OPI can disseminate any important information to the Network.